It is the aim of this observation trial to confirm the results of the bnhl bfm 95 trial through an optimized, consistent treatment strategy for children and adolescents. Treatment protocol of the nhlbfm and the nopho study groups. Soluble interleukin2 receptor is a sensitive diagnostic test in adult hlh. The cumulative experiences from hlh 94 and other studies have led to the development of a new treatment protocol presented here, hlh 2004, which includesupdateddiagnosticand therapeutic guidelines from the. We would like to show you a description here but the site wont allow us. Treatment protocol for hemophagocytic lymphohistiocytosis 2004. Treatment of hemophagocytic lymphohistiocytosis with. Treatment protocol for hemophagocytic lymphohistiocytosis 2004 the safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
Treatment of hemophagocytic lymphohistiocytosis with hlh. Management is largely based on hlh 2004 protocol for secondary cases and almost all cases of primary hlh. Listing a study does not mean it has been evaluated by the u. Eligibility criteria for this study were as follows. Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Filipovich, helmut gadner, shinsaku imashuku, diane komp, stephan ladisch, david webb, and gritta janka, for the histiocyte. The nhl15 protocol is a novel, doseintense, dosedense, sequential. Hlh2004 protocol and allogeneic haematopoietic stem cell transplantation. Henter ji1, horne a, arico m, egeler rm, filipovich ah, imashuku s, ladisch s, mcclain k, webb d, winiarski j, janka g. The nhl15 protocol for aggressive nonhodgkins lymphomas. Bc cancer protocol summary for treatment of hemophagocytic.
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